HEF1 (NEDD9) (NM_001142393) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Synonyms
CAS-L; CAS2; CASL; CASS2; HEF1
Gene ID
4739
UniProt
Q14511, A0A024QZV9
Accession Number mRNA
NM_001142393
Chromosomal Location
6p24.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
92.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NEDD9
Species
Human
Protein ID
NP_001135865
Overview
Recombinant protein of human neural precursor cell expressed, developmentally down-regulated 9 (NEDD9), transcript variant 3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4739
Uniprot URL
https://www.uniprot.org/uniprot/Q14511
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001142393
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001135865
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