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EXOC7 (NM_001145299) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required for assembly of the exocyst complex and docking of the complex to the plasma membrane. The encoded protein may also play a role in pre-mRNA splicing through interactions with pre-mRNA-processing factor 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Nov 2011]

Overview

Purified recombinant protein of Homo sapiens exocyst complex component 7 (EXOC7), transcript variant 6

Synonyms

2-5-3p; BLOM4; EX070; EXO70; Exo70p; EXOC1; NEDSEBA; YJL085W

Gene ID

23265

UniProt

Q9UPT5, Q63HP7

Accession Number mRNA

NM_001145299

Chromosomal Location

17q25.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Insulin signaling pathway

Field of Research

Insulin signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

80.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

EXOC7

Species

Human

Protein ID

NP_001138771

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/23265

Uniprot URL

https://www.uniprot.org/uniprot/Q9UPT5

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001145299

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001138771

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