Kallikrein 11 (KLK11) (NM_001136032) Human Recombinant Protein
Product Specifications
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing and the use of alternate promoters results in multiple transcript variants encoding distinct isoforms which are differentially expressed. [provided by RefSeq, Dec 2016]
Overview
Recombinant protein of human kallikrein-related peptidase 11 (KLK11), transcript variant 1 prepropr
Synonyms
PRSS20; TLSP
Gene ID
11012
UniProt
Q9UBX7, A0A1R3UDR5, Q9UBX7-1
Accession Number mRNA
NM_001136032
Chromosomal Location
19q13.41
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protease, Secreted Protein
Molecular Weight
27.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KLK11
Species
Human
Protein ID
NP_001129504
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11012
Uniprot URL
https://www.uniprot.org/uniprot/Q9UBX7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001136032
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001129504
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