SMAD6 (NM_001142861) Human Recombinant Protein
Selected Variant
PH33282M5
Size: 20 µg
Product Specifications
Background
The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene.[provided by RefSeq, Sep 2014]
Overview
Recombinant protein of human SMAD family member 6 (SMAD6), transcript variant 2
Synonyms
AOVD2; HsT17432; MADH6; MADH7
Gene ID
4091
UniProt
O43541
Accession Number mRNA
NM_001142861
Chromosomal Location
15q22.31
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
TGF-beta signaling pathway
Field of Research
TGF-beta signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors
Molecular Weight
26.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SMAD6
Species
Human
Protein ID
NP_001136333
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4091
Uniprot URL
https://www.uniprot.org/uniprot/O43541
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001142861
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001136333
Price
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