RASGRP3 (NM_001139488) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers. [provided by RefSeq, Mar 2017]

Overview

Recombinant protein of human RAS guanyl releasing protein 3 (calcium and DAG-regulated) (RASGRP3), transcript variant 2

Synonyms

GRP3

Gene ID

25780

UniProt

Q8IV61

Accession Number mRNA

NM_001139488

Chromosomal Location

2p22.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

B cell receptor signaling pathway, MAPK signaling pathway

Field of Research

B cell receptor signaling pathway, MAPK signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

78.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.