RASGRP3 (NM_001139488) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers. [provided by RefSeq, Mar 2017]
Overview
Recombinant protein of human RAS guanyl releasing protein 3 (calcium and DAG-regulated) (RASGRP3), transcript variant 2
Synonyms
GRP3
Gene ID
25780
UniProt
Q8IV61
Accession Number mRNA
NM_001139488
Chromosomal Location
2p22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
B cell receptor signaling pathway, MAPK signaling pathway
Field of Research
B cell receptor signaling pathway, MAPK signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
78.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RASGRP3
Species
Human
Protein ID
NP_001132960
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/25780
Uniprot URL
https://www.uniprot.org/uniprot/Q8IV61
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001139488
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001132960
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