Alpha smooth muscle Actin (ACTA2) (NM_001141945) Human Recombinant Protein
Product Specifications
Background
This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome. [provided by RefSeq, Sep 2017]
Overview
Recombinant protein of human actin, alpha 2, smooth muscle, aorta (ACTA2), transcript variant 1
Synonyms
AAT6; ACTSA; MYMY5
Gene ID
59
UniProt
P62736, D2JYH4
Accession Number mRNA
NM_001141945
Chromosomal Location
10q23.31
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Vascular smooth muscle contraction
Field of Research
Vascular smooth muscle contraction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
27991922
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
41.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ACTA2
Species
Human
Protein ID
NP_001135417
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/59
Uniprot URL
https://www.uniprot.org/uniprot/P62736
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001141945
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001135417
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