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DACH2 (NM_001139515) Human Recombinant Protein

Product Specifications

Background

This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]

Synonyms

FLJ31391; MGC138545

Gene ID

117154

UniProt

Q96NX9, A8K3I1

Accession Number mRNA

NM_001139515

Chromosomal Location

Xq21.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transcription Factors

Molecular Weight

47 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

DACH2

Species

Human

Protein ID

NP_001132987

Overview

Recombinant protein of human dachshund homolog 2 (Drosophila) (DACH2), transcript variant 3

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/117154

Uniprot URL

https://www.uniprot.org/uniprot/Q96NX9

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001139515

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001132987

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