DACH2 (NM_001139515) Human Recombinant Protein
Product Specifications
Background
This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
Synonyms
FLJ31391; MGC138545
Gene ID
117154
UniProt
Q96NX9, A8K3I1
Accession Number mRNA
NM_001139515
Chromosomal Location
Xq21.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
47 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DACH2
Species
Human
Protein ID
NP_001132987
Overview
Recombinant protein of human dachshund homolog 2 (Drosophila) (DACH2), transcript variant 3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/117154
Uniprot URL
https://www.uniprot.org/uniprot/Q96NX9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001139515
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001132987
Curated Selection
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