Periostin (POSTN) (NM_001135935) Human Recombinant Protein
Product Specifications
Background
This gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
Synonyms
OSF-2; OSF2; PDLPOSTN; PN
Gene ID
10631
UniProt
Q15063
Accession Number mRNA
NM_001135935
Chromosomal Location
13q13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein
Molecular Weight
87.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
POSTN
Species
Human
Protein ID
NP_001129407
Overview
Recombinant protein of human periostin, osteoblast specific factor (POSTN), transcript variant 3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10631
Uniprot URL
https://www.uniprot.org/uniprot/Q15063
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001135935
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001129407
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