Sex Hormone Binding Globulin (SHBG) (NM_001146279) Human Recombinant Protein
Product Specifications
Background
This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Synonyms
ABP; SBP; TEBG
Gene ID
6462
UniProt
P04278, B0FWH2
Accession Number mRNA
NM_001146279
Chromosomal Location
17p13.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein
Molecular Weight
38.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SHBG
Species
Human
Protein ID
NP_001139751
Overview
Recombinant protein of human sex hormone-binding globulin (SHBG), transcript variant 2.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6462
Uniprot URL
https://www.uniprot.org/uniprot/P04278
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001146279
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001139751
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