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Sex Hormone Binding Globulin (SHBG) (NM_001146279) Human Recombinant Protein

Selected Variant

PH33194M5

Size: 20 µg

Product Specifications

Background

This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Overview

Recombinant protein of human sex hormone-binding globulin (SHBG), transcript variant 2.

Synonyms

ABP; SBP; TEBG

Gene ID

6462

UniProt

P04278, B0FWH2

Accession Number mRNA

NM_001146279

Chromosomal Location

17p13.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Secreted Protein

Molecular Weight

38.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SHBG

Species

Human

Protein ID

NP_001139751

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6462

Uniprot URL

https://www.uniprot.org/uniprot/P04278

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001146279

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001139751

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