LMO2 (NM_005574) Human Recombinant Protein
Product Specifications
Background
LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Nov 2008]
Synonyms
LMO-2; RBTN2; RBTNL1; RHOM2; TTG2
Gene ID
4005
UniProt
P25791
Accession Number mRNA
NM_005574
Chromosomal Location
11p13
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
24.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
LMO2
Species
Human
Protein ID
NP_005565
Overview
Recombinant protein of human LIM domain only 2 (rhombotin-like 1) (LMO2), transcript variant 1.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4005
Uniprot URL
https://www.uniprot.org/uniprot/P25791
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005574
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005565
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