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G CSF (CSF3) (NM_001178147) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the IL-6 superfamily of cytokines. The encoded cytokine controls the production, differentiation, and function of granulocytes. Granulocytes are a type of white blood cell that are part of the innate immune response. A modified form of this protein is commonly administered to manage chemotherapy-induced neutropenia. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2020]

Synonyms

C17orf33; CSF3OS; GCSF

Gene ID

1440

UniProt

P09919, Q8N4W3

Accession Number mRNA

NM_001178147

Chromosomal Location

17q21.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway

Field of Research

Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein

Molecular Weight

18.6

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CSF3

Species

Human

Protein ID

NP_001171618

Overview

Purified recombinant protein of Homo sapiens colony stimulating factor 3 (granulocyte) (CSF3), transcript variant 4.

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/1440

Uniprot URL

https://www.uniprot.org/uniprot/P09919

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001178147

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001171618

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