CFHR3 (NM_001166624) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Overview
Purified recombinant protein of Homo sapiens complement factor H-related 3 (CFHR3), transcript variant 2.
Synonyms
CFHL3; DOWN16; FHR-3; FHR3; HLF4
Gene ID
10878
UniProt
Q02985
Accession Number mRNA
NM_001166624
Chromosomal Location
1q31.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Secreted Protein
Molecular Weight
31.2
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CFHR3
Species
Human
Protein ID
NP_001160096
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10878
Uniprot URL
https://www.uniprot.org/uniprot/Q02985
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001166624
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001160096
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