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CD244 (NM_001166664) Human Recombinant Protein

Product Specifications

Background

This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]

Synonyms

2B4; NAIL; NKR2B4; Nmrk; SLAMF4

Gene ID

51744

UniProt

Q9BZW8

Accession Number mRNA

NM_001166664

Chromosomal Location

1q23.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Natural killer cell mediated cytotoxicity

Field of Research

Natural killer cell mediated cytotoxicity

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

Molecular Weight

31.2

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CD244

Species

Human

Protein ID

NP_001160136

Overview

Purified recombinant protein of Homo sapiens CD244 molecule, natural killer cell receptor 2B4 (CD244), transcript variant 3.

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/51744

Uniprot URL

https://www.uniprot.org/uniprot/Q9BZW8

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001166664

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001160136

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