CD244 (NM_001166664) Human Recombinant Protein
Product Specifications
Background
This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
Overview
Purified recombinant protein of Homo sapiens CD244 molecule, natural killer cell receptor 2B4 (CD244), transcript variant 3.
Synonyms
2B4; NAIL; NKR2B4; Nmrk; SLAMF4
Gene ID
51744
UniProt
Q9BZW8
Accession Number mRNA
NM_001166664
Chromosomal Location
1q23.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Natural killer cell mediated cytotoxicity
Field of Research
Natural killer cell mediated cytotoxicity
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Molecular Weight
31.2
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CD244
Species
Human
Protein ID
NP_001160136
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/51744
Uniprot URL
https://www.uniprot.org/uniprot/Q9BZW8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001166664
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001160136
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