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OSMR (NM_001168355) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Synonyms

IL-31R-beta; IL-31RB; OSMRB; OSMRbeta; PLCA1

Gene ID

9180

UniProt

Q99650

Accession Number mRNA

NM_001168355

Chromosomal Location

5p13.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Field of Research

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transmembrane

Molecular Weight

40

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

OSMR

Species

Human

Protein ID

NP_001161827

Overview

Recombinant protein of human oncostatin M receptor (OSMR), transcript variant 2

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9180

Uniprot URL

https://www.uniprot.org/uniprot/Q99650

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001168355

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001161827

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