ATXN10 (NM_001167621) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of an ATTCT repeat from 9-32 copies to 800-4500 copies in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jul 2016]
Overview
Recombinant protein of human ataxin 10 (ATXN10), transcript variant 2.
Synonyms
E46L; HUMEEP; SCA10
Gene ID
25814
UniProt
Q9UBB4, A6NLC4
Accession Number mRNA
NM_001167621
Chromosomal Location
22q13.31
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
46.7
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ATXN10
Species
Human
Protein ID
NP_001161093
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/25814
Uniprot URL
https://www.uniprot.org/uniprot/Q9UBB4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001167621
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001161093
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