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ATXN10 (NM_001167621) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of an ATTCT repeat from 9-32 copies to 800-4500 copies in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jul 2016]

Overview

Recombinant protein of human ataxin 10 (ATXN10), transcript variant 2.

Synonyms

E46L; HUMEEP; SCA10

Gene ID

25814

UniProt

Q9UBB4, A6NLC4

Accession Number mRNA

NM_001167621

Chromosomal Location

22q13.31

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

46.7

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ATXN10

Species

Human

Protein ID

NP_001161093

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/25814

Uniprot URL

https://www.uniprot.org/uniprot/Q9UBB4

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001167621

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001161093

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