MAN1 (LEMD3) (NM_001167614) Human Recombinant Protein
Product Specifications
Background
This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.[provided by RefSeq, Nov 2009]
Overview
Recombinant protein of human LEM domain containing 3 (LEMD3), transcript variant 2.
Synonyms
MAN1
Gene ID
23592
UniProt
Q9Y2U8
Accession Number mRNA
NM_001167614
Chromosomal Location
12q14.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
100.3
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
LEMD3
Species
Human
Protein ID
NP_001161086
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/23592
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y2U8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001167614
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001161086
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