CLDN24 (NM_001185149) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is 75% identical to the mouse homolog. This gene is upstream of the CLDN22 gene, which overlaps the WWC2 gene on the opposite strand in the genome.[provided by RefSeq, Aug 2010]
Synonyms
CLDN21
Gene ID
100132463
UniProt
A6NM45
Accession Number mRNA
NM_001185149
Chromosomal Location
4q35.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
24.9
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CLDN24
Species
Human
Protein ID
NP_001172078
Overview
Recombinant protein of human claudin 24 (CLDN24)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/100132463
Uniprot URL
https://www.uniprot.org/uniprot/A6NM45
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001185149
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001172078
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