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Chromogranin A (CHGA) (NM_001275) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]

Synonyms

CGA

Gene ID

1113

UniProt

P10645, Q86T07

Accession Number mRNA

NM_001275

Chromosomal Location

14q32.12

Expression System

HEK293

Tag

C-HIS

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

PBS, pH7.4, 10% glycerol.

Function

Druggable Genome, Secreted Protein

Molecular Weight

50.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CHGA

Species

Human

Protein ID

NP_001266

Overview

Purified recombinant protein of Human chromogranin A (parathyroid secretory protein 1) (CHGA), Leu19-End, with C-terminal His tag, secretory expressed in HEK293 cells, 50ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/1113

Uniprot URL

https://www.uniprot.org/uniprot/P10645

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001275

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001266

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