Chromogranin A (CHGA) (NM_001275) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
Synonyms
CGA
Gene ID
1113
UniProt
P10645, Q86T07
Accession Number mRNA
NM_001275
Chromosomal Location
14q32.12
Expression System
HEK293
Tag
C-HIS
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
PBS, pH7.4, 10% glycerol.
Function
Druggable Genome, Secreted Protein
Molecular Weight
50.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CHGA
Species
Human
Protein ID
NP_001266
Overview
Purified recombinant protein of Human chromogranin A (parathyroid secretory protein 1) (CHGA), Leu19-End, with C-terminal His tag, secretory expressed in HEK293 cells, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1113
Uniprot URL
https://www.uniprot.org/uniprot/P10645
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001275
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001266
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