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Secretogranin V (SCG5) (NM_003020) Human Recombinant Protein

Product Specifications

Background

This gene encodes a secreted chaperone protein that prevents the aggregation of other secreted proteins, including proteins that are associated with neurodegenerative and metabolic disease. The encoded protein may be best known for its role in the trafficking and activation of prohormone convertase PC2 (encoded by Gene ID: 5126) . Phosphorylation of the encoded protein has been shown to have an inhibitory effect on its chaperone function. This gene also produces a ARHGAP11A-SCG5 readthrough transcript and ARHGAP11A-SCG5 protein. [provided by RefSeq, Feb 2019]

Overview

Purified recombinant protein of Human secretogranin V (7B2 protein) (SCG5), Tyr27-End, with C-terminal His tag, secretory expressed in HEK293 cells, 50 ug

Synonyms

7B2; P7B2; SGNE1; SgV

Gene ID

6447

UniProt

P05408

Accession Number mRNA

NM_003020

Chromosomal Location

15q13.3

Expression System

HEK293

Tag

C-HIS

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

PBS, pH7.4, 10% glycerol

Function

Secreted Protein

Molecular Weight

22.1kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SCG5

Species

Human

Protein ID

NP_003011

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6447

Uniprot URL

https://www.uniprot.org/uniprot/P05408

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_003020

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003011

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