Secretogranin V (SCG5) (NM_003020) Human Recombinant Protein
Product Specifications
Background
This gene encodes a secreted chaperone protein that prevents the aggregation of other secreted proteins, including proteins that are associated with neurodegenerative and metabolic disease. The encoded protein may be best known for its role in the trafficking and activation of prohormone convertase PC2 (encoded by Gene ID: 5126) . Phosphorylation of the encoded protein has been shown to have an inhibitory effect on its chaperone function. This gene also produces a ARHGAP11A-SCG5 readthrough transcript and ARHGAP11A-SCG5 protein. [provided by RefSeq, Feb 2019]
Synonyms
7B2; P7B2; SGNE1; SgV
Gene ID
6447
UniProt
P05408
Accession Number mRNA
NM_003020
Chromosomal Location
15q13.3
Expression System
HEK293
Tag
C-HIS
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
PBS, pH7.4, 10% glycerol
Function
Secreted Protein
Molecular Weight
22.1kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SCG5
Species
Human
Protein ID
NP_003011
Overview
Purified recombinant protein of Human secretogranin V (7B2 protein) (SCG5), Tyr27-End, with C-terminal His tag, secretory expressed in HEK293 cells, 50 ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6447
Uniprot URL
https://www.uniprot.org/uniprot/P05408
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003020
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003011
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