APELA (NM_001297550) Human Recombinant Protein

Product Specifications

Background

This gene encodes a peptide hormone that binds to the Apelin receptor. The encoded protein is required for heart development in zebrafish and has been shown to maintain self-renewal of human embryonic stem cells through activation of the PI3K/AKT pathway. Experiments in human and mouse cell lines point to additional roles for the encoded protein in angiogenesis and regulation of vascular tone. [provided by RefSeq, Jul 2016]

Overview

Purified recombinant protein of Human apelin receptor early endogenous ligand (APELA), Gln23-End, with C-terminal His tag, secretory expressed in HEK293 cells, 50 ug

Synonyms

ELA; Ende; tdl

Gene ID

100506013

UniProt

P0DMC3, X5D2P3

Accession Number mRNA

NM_001297550

Chromosomal Location

4q32.3

Expression System

HEK293

Tag

C-HIS

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

PBS, pH7.4, 10% glycerol

Molecular Weight

5.3kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.