APELA (NM_001297550) Human Recombinant Protein
Product Specifications
Background
This gene encodes a peptide hormone that binds to the Apelin receptor. The encoded protein is required for heart development in zebrafish and has been shown to maintain self-renewal of human embryonic stem cells through activation of the PI3K/AKT pathway. Experiments in human and mouse cell lines point to additional roles for the encoded protein in angiogenesis and regulation of vascular tone. [provided by RefSeq, Jul 2016]
Overview
Purified recombinant protein of Human apelin receptor early endogenous ligand (APELA), Gln23-End, with C-terminal His tag, secretory expressed in HEK293 cells, 50 ug
Synonyms
ELA; Ende; tdl
Gene ID
100506013
UniProt
P0DMC3, X5D2P3
Accession Number mRNA
NM_001297550
Chromosomal Location
4q32.3
Expression System
HEK293
Tag
C-HIS
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
PBS, pH7.4, 10% glycerol
Molecular Weight
5.3kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
APELA
Species
Human
Protein ID
NP_001284479
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/100506013
Uniprot URL
https://www.uniprot.org/uniprot/P0DMC3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001297550
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001284479
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