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XYLT1 (NM_022166) Human Recombinant Protein

Product Specifications

Background

This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum.[provided by RefSeq, Nov 2009]

Synonyms

DBQD2; PXYLT1; XT-I; XT1; XTI; xylT-I; XYLTI

Gene ID

64131

UniProt

Q86Y38

Accession Number mRNA

NM_022166

Chromosomal Location

16p12.3

Expression System

HEK293

Tag

C-HIS

Related Pathways

Chondroitin sulfate biosynthesis, Heparan sulfate biosynthesis, Metabolic pathways

Field of Research

Chondroitin sulfate biosynthesis, Heparan sulfate biosynthesis, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

PBS, pH7.4, 10% glycerol

Function

Transmembrane

Molecular Weight

108.9kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

XYLT1

Species

Human

Protein ID

NP_071449

Overview

Purified recombinant protein of Human xylosyltransferase I (XYLT1), full length, with C-terminal His tag, secretory expressed in HEK293 cells, 50ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/64131

Uniprot URL

https://www.uniprot.org/uniprot/Q86Y38

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_022166

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_071449

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