Myeloperoxidase (MPO) (NM_000250) Human Recombinant Protein
Product Specifications
Background
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]
Synonyms
Myeloperoxidase
Gene ID
4353
UniProt
P05164
Accession Number mRNA
NM_000250
Chromosomal Location
17q22
Expression System
HEK293
Tag
N-HIS
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
PBS, pH7.4, 10% glycerol
Function
Druggable Genome
Molecular Weight
67.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MPO
Species
Human
Protein ID
NP_000241
Overview
Purified recombinant protein of Human myeloperoxidase (MPO), Ser155-End, with N-terminal His tag, secretory expressed in HEK293 cells, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4353
Uniprot URL
https://www.uniprot.org/uniprot/P05164
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000250
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000241
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