Myeloperoxidase (MPO) (NM_000250) Human Recombinant Protein

Product Specifications

Background

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]

Overview

Purified recombinant protein of Human myeloperoxidase (MPO), Ser155-End, with N-terminal His tag, secretory expressed in HEK293 cells, 50ug

Synonyms

Myeloperoxidase

Gene ID

4353

UniProt

P05164

Accession Number mRNA

NM_000250

Chromosomal Location

17q22

Expression System

HEK293

Tag

N-HIS

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

PBS, pH7.4, 10% glycerol

Function

Druggable Genome

Molecular Weight

67.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.