TRIM28 Mutant (K779R) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq, Jul 2008]

Overview

Purified mutant recombinant protein of Human tripartite motif containing 28 (TRIM28), mutation at ((K779R)

Synonyms

KAP1; PPP1R157; RNF96; TF1B; TIF1B

Gene ID

10155

Accession Number mRNA

NM_005762

Chromosomal Location

19q13.43

Expression System

HEK293

Tag

Myc-DDK

Concentration

>50 ug/mL as determined by microplate Bradford method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Protein Kinase, Stem cell - Pluripotency, Transcription Factors

Molecular Weight

88.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.