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ASB2 (NM_016150) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Overview

Purified recombinant protein of Human ankyrin repeat and SOCS box containing 2 (ASB2), transcript variant 2, Met1-Gly300, with N-terminal His tag, expressed in E.coli, 50ug

Synonyms

ASB-2

Gene ID

51676

UniProt

Q96Q27

Accession Number mRNA

NM_016150

Chromosomal Location

14q32.12

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Function

Druggable Genome

Molecular Weight

32.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ASB2

Species

Human

Protein ID

NP_057234

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/51676

Uniprot URL

https://www.uniprot.org/uniprot/Q96Q27

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_016150

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_057234

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