NEK2 (NM_002497) Human Recombinant Protein
Product Specifications
Background
This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene. [provided by RefSeq, Feb 2011]
Overview
Purified recombinant protein of Human NIMA (never in mitosis gene a) -related kinase 2 (NEK2), transcript variant 1, Met1-Tyr240, with N-terminal His tag, expressed in E.coli, 50ug
Synonyms
HsPK21; NEK2A; NLK1; PPP1R111; RP67
Gene ID
4751
UniProt
P51955
Accession Number mRNA
NM_002497
Chromosomal Location
1q32.3
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Function
Druggable Genome, Protein Kinase
Molecular Weight
27.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NEK2
Species
Human
Protein ID
NP_002488
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4751
Uniprot URL
https://www.uniprot.org/uniprot/P51955
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002497
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002488
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