SARA (ZFYVE9) (NM_004799) Human Recombinant Protein

Product Specifications

Background

This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. The encoded protein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to the TGFB receptor. There are multiple pseudogenes for this gene on chromosomes 2, 15, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

Overview

Purified recombinant protein of Human zinc finger, FYVE domain containing 9 (ZFYVE9), transcript variant 3, Asp699-Ile899, with N-terminal His tag, expressed in E.coli, 50ug

Synonyms

MADHIP; NSP; PPP1R173; SARA; SMADIP

Gene ID

9372

UniProt

O95405

Accession Number mRNA

NM_004799

Chromosomal Location

1p32.3

Expression System

E. coli

Tag

N-His

Related Pathways

TGF-beta signaling pathway

Field of Research

TGF-beta signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Molecular Weight

21.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.