Neuritin (NRN1) (NM_016588) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI) -anchored proteins. The encoded protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Synonyms
DJ380B8.2; NRN
Gene ID
51299
UniProt
Q9NPD7
Accession Number mRNA
NM_016588
Chromosomal Location
6p25.1
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Molecular Weight
12.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NRN1
Species
Human
Protein ID
NP_057672
Overview
Purified recombinant protein of Human neuritin 1 (NRN1), Ala28-End, with N-terminal His tag, expressed in E.coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/51299
Uniprot URL
https://www.uniprot.org/uniprot/Q9NPD7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_016588
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_057672
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