CFHR3 (NM_021023) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Overview

Purified recombinant protein of Human complement factor H-related 3 (CFHR3), transcript variant 1, Gln19-End, with N-terminal His tag, expressed in E.coli, 50ug

Synonyms

CFHL3; DOWN16; FHR-3; FHR3; HLF4

Gene ID

10878

UniProt

Q02985

Accession Number mRNA

NM_021023

Chromosomal Location

1q31.3

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Function

Secreted Protein

Molecular Weight

35.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.