VAP1 (AOC3) (NM_003734) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]

Overview

Purified recombinant protein of Human amine oxidase, copper containing 3 (vascular adhesion protein 1) (AOC3), Gly27-Pro256, with N-terminal His tag, expressed in E.coli, 50ug

Synonyms

HPAO; SSAO; VAP-1; VAP1

Gene ID

8639

UniProt

Q16853, Q9UEU7

Accession Number mRNA

NM_003734

Chromosomal Location

17q21.31

Expression System

E. coli

Tag

N-His

Related Pathways

Beta-Alanine metabolism, Glycine, serine and threonine metabolism, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism

Field of Research

Beta-Alanine metabolism, Glycine, serine and threonine metabolism, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Function

Transmembrane

Molecular Weight

25.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.