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FGF10 (NM_004465) Human Recombinant Protein

Selected Variant

PH30248E1

Size: 50 µg

Product Specifications

Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human fibroblast growth factor 10 (FGF10), Gln38-End, with N-terminal His tag, expressed in E.coli, 50ug

Synonyms

Fibroblast growth factor 10; keratinocyte growth factor 2; produced by fibroblasts of urinary bladder lamina propria

Gene ID

2255

UniProt

O15520

Accession Number mRNA

NM_004465

Chromosomal Location

5p12

Expression System

E. coli

Tag

N-His

Related Pathways

MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

Field of Research

MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Function

Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Secreted Protein, Transcription Factors, Transmembrane

Molecular Weight

19.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FGF10

Species

Human

Protein ID

NP_004456

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2255

Uniprot URL

https://www.uniprot.org/uniprot/O15520

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004465

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004456

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