ECT2 (NM_018098) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]
Synonyms
ARHGEF31
Gene ID
1894
UniProt
Q9H8V3
Accession Number mRNA
NM_018098
Chromosomal Location
3q26.31
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Function
Druggable Genome
Molecular Weight
30.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ECT2
Species
Human
Protein ID
NP_060568
Overview
Purified recombinant protein of Human epithelial cell transforming sequence 2 oncogene (ECT2), Ile175-Asn438, with N-terminal His tag, expressed in E.coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1894
Uniprot URL
https://www.uniprot.org/uniprot/Q9H8V3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_018098
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060568
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