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ECT2 (NM_018098) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]

Overview

Purified recombinant protein of Human epithelial cell transforming sequence 2 oncogene (ECT2), Ile175-Asn438, with N-terminal His tag, expressed in E.coli, 50ug

Synonyms

ARHGEF31

Gene ID

1894

UniProt

Q9H8V3

Accession Number mRNA

NM_018098

Chromosomal Location

3q26.31

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Function

Druggable Genome

Molecular Weight

30.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ECT2

Species

Human

Protein ID

NP_060568

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/1894

Uniprot URL

https://www.uniprot.org/uniprot/Q9H8V3

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_018098

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_060568

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