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Eotaxin 3 (CCL26) (NM_006072) Human Recombinant Protein

Product Specifications

Background

This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. This protein also has antimicrobial activity, displaying an antibacterial effect on S. pneumoniae, S. aureus, Non-typeable H. influenzae, and P. aeruginosa. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2020]

Synonyms

IMAC; MIP-4a; MIP-4alpha; SCYA26; TSC-1

Gene ID

10344

UniProt

Q9Y258

Accession Number mRNA

NM_006072

Chromosomal Location

7q11.23

Expression System

E. coli

Tag

N-His

Related Pathways

Chemokine signaling pathway, Cytokine-cytokine receptor interaction

Field of Research

Chemokine signaling pathway, Cytokine-cytokine receptor interaction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Function

Druggable Genome, Secreted Protein

Molecular Weight

8.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CCL26

Species

Human

Protein ID

NP_006063

Overview

Purified recombinant protein of Human chemokine (C-C motif) ligand 26 (CCL26), Thr24-End, with N-terminal His tag, expressed in E.coli, 50ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/10344

Uniprot URL

https://www.uniprot.org/uniprot/Q9Y258

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_006072

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_006063

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