NSD3 (WHSC1L1) (NM_017778) Human Recombinant Protein

Product Specifications

Background

This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described. [provided by RefSeq, May 2015]

Overview

Purified recombinant protein of Human Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1), transcript variant short, Asn427-Ser566, with N-terminal His-ABP tag, expressed in E.coli, 50ug

Synonyms

KMT3F; KMT3G; pp14328; WHISTLE; WHSC1L1

Gene ID

54904

UniProt

Q9BZ95

Accession Number mRNA

NM_017778

Chromosomal Location

8p11.23

Expression System

E. coli

Tag

N-His ABP

Related Pathways

Lysine degradation

Field of Research

Lysine degradation

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Function

Druggable Genome, Transcription Factors

Molecular Weight

30.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.