TRPC5 (NM_012471) Human Recombinant Protein

Product Specifications

Background

This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na (+) -H+ exchange regulatory factor (NHERF), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1) . [provided by RefSeq, May 2010]

Overview

Purified recombinant protein of Human transient receptor potential cation channel, subfamily C, member 5 (TRPC5), Pro812-His927, with N-terminal His-ABP tag, expressed in E.coli, 50ug

Synonyms

PPP1R159; TRP5

Gene ID

7224

UniProt

Q9UL62

Accession Number mRNA

NM_012471

Chromosomal Location

Xq23

Expression System

E. coli

Tag

N-His ABP

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Function

Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane

Molecular Weight

28.0 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.