TRPC5 (NM_012471) Human Recombinant Protein
Product Specifications
Background
This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na (+) -H+ exchange regulatory factor (NHERF), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1) . [provided by RefSeq, May 2010]
Synonyms
PPP1R159; TRP5
Gene ID
7224
UniProt
Q9UL62
Accession Number mRNA
NM_012471
Chromosomal Location
Xq23
Expression System
E. coli
Tag
N-His ABP
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Function
Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
Molecular Weight
28.0 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TRPC5
Species
Human
Protein ID
NP_036603
Overview
Purified recombinant protein of Human transient receptor potential cation channel, subfamily C, member 5 (TRPC5), Pro812-His927, with N-terminal His-ABP tag, expressed in E.coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7224
Uniprot URL
https://www.uniprot.org/uniprot/Q9UL62
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_012471
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_036603
Curated Selection
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