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KRTHB3 (KRT83) (NM_002282) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human keratin 83 (KRT83), full length, with N-terminal His tag, expressed in E.coli, 50ug

Synonyms

EKVP5; Hb-3; HB3; KRTHB3; MNLIX

Gene ID

3889

UniProt

P78385

Accession Number mRNA

NM_002282

Chromosomal Location

12q13.13

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Molecular Weight

54.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

KRT83

Species

Human

Protein ID

NP_002273

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3889

Uniprot URL

https://www.uniprot.org/uniprot/P78385

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002282

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002273

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