Anillin (ANLN) (NM_018685) Human Recombinant Protein

Product Specifications

Background

This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]

Overview

Purified recombinant protein of Human anillin, actin binding protein (ANLN), Thr900-Lys1124, with N-terminal His tag, expressed in E.coli, 50ug

Synonyms

FSGS8; scra; Scraps

Gene ID

54443

UniProt

Q9NQW6, A0A024RA49

Accession Number mRNA

NM_018685

Chromosomal Location

7p14.2

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Function

Druggable Genome

Molecular Weight

25.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.