Anillin (ANLN) (NM_018685) Human Recombinant Protein
Product Specifications
Background
This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
Synonyms
FSGS8; scra; Scraps
Gene ID
54443
UniProt
Q9NQW6, A0A024RA49
Accession Number mRNA
NM_018685
Chromosomal Location
7p14.2
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Function
Druggable Genome
Molecular Weight
25.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ANLN
Species
Human
Protein ID
NP_061155
Overview
Purified recombinant protein of Human anillin, actin binding protein (ANLN), Thr900-Lys1124, with N-terminal His tag, expressed in E.coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/54443
Uniprot URL
https://www.uniprot.org/uniprot/Q9NQW6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_018685
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_061155
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