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Cyclin G2 (CCNG2) (NM_004354) Human Recombinant Protein

Product Specifications

Background

The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human cyclin G2 (CCNG2), full length, with N-terminal His tag, expressed in E.coli, 50ug

Synonyms

Cyclin G2; OTTHUMP00000160592

Gene ID

901

UniProt

Q16589, A0A024RDC7

Accession Number mRNA

NM_004354

Chromosomal Location

4q21.1

Expression System

E. coli

Tag

N-His

Related Pathways

P53 signaling pathway

Field of Research

P53 signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Function

Druggable Genome

Molecular Weight

38.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CCNG2

Species

Human

Protein ID

NP_004345

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/901

Uniprot URL

https://www.uniprot.org/uniprot/Q16589

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004354

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004345

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