Cyclin G2 (CCNG2) (NM_004354) Human Recombinant Protein
Product Specifications
Background
The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle. [provided by RefSeq, Jul 2008]
Synonyms
Cyclin G2; OTTHUMP00000160592
Gene ID
901
UniProt
Q16589, A0A024RDC7
Accession Number mRNA
NM_004354
Chromosomal Location
4q21.1
Expression System
E. coli
Tag
N-His
Related Pathways
P53 signaling pathway
Field of Research
P53 signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Function
Druggable Genome
Molecular Weight
38.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CCNG2
Species
Human
Protein ID
NP_004345
Overview
Purified recombinant protein of Human cyclin G2 (CCNG2), full length, with N-terminal His tag, expressed in E.coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/901
Uniprot URL
https://www.uniprot.org/uniprot/Q16589
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004354
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004345
Curated Selection
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