RhoGAP (ARHGAP5) (NM_001173) Human Recombinant Protein
Product Specifications
Background
Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Overview
Purified recombinant protein of Human Rho GTPase activating protein 5 (ARHGAP5), transcript variant 2, Ser948-Met1261, with N-terminal His tag, expressed in E.coli, 50ug
Synonyms
GFI2; p190-B; p190BRhoGAP; RhoGAP5
Gene ID
394
UniProt
Q13017
Accession Number mRNA
NM_001173
Chromosomal Location
14q12
Expression System
E. coli
Tag
N-His
Related Pathways
Focal adhesion, Leukocyte transendothelial migration
Field of Research
Focal adhesion, Leukocyte transendothelial migration
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 8M Urea
Molecular Weight
36.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ARHGAP5
Species
Human
Protein ID
NP_001164
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/394
Uniprot URL
https://www.uniprot.org/uniprot/Q13017
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001173
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001164
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