RhoGAP (ARHGAP5) (NM_001173) Human Recombinant Protein

Product Specifications

Background

Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human Rho GTPase activating protein 5 (ARHGAP5), transcript variant 2, Ser948-Met1261, with N-terminal His tag, expressed in E.coli, 50ug

Synonyms

GFI2; p190-B; p190BRhoGAP; RhoGAP5

Gene ID

394

UniProt

Q13017

Accession Number mRNA

NM_001173

Chromosomal Location

14q12

Expression System

E. coli

Tag

N-His

Related Pathways

Focal adhesion, Leukocyte transendothelial migration

Field of Research

Focal adhesion, Leukocyte transendothelial migration

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, pH8.0, 8M Urea

Molecular Weight

36.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.