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EPX (NM_000502) Human Recombinant Protein

Product Specifications

Background

This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded preproprotein is proteolytically processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a gene cluster with other peroxidase genes on chromosome 17. Mutations in this gene result in eosinophil peroxidase deficiency. [provided by RefSeq, Feb 2016]

Overview

Purified recombinant protein of Human eosinophil peroxidase (EPX), Arg140-Met422, with N-terminal His tag, expressed in E.coli, 50ug

Synonyms

EPO; EPP; EPX-PEN; EPXD

Gene ID

8288

UniProt

P11678

Accession Number mRNA

NM_000502

Chromosomal Location

17q22

Expression System

E. coli

Tag

N-His

Related Pathways

Asthma

Field of Research

Asthma

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, pH8.0, 8M Urea

Function

Druggable Genome

Molecular Weight

32.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

EPX

Species

Human

Protein ID

NP_000493

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/8288

Uniprot URL

https://www.uniprot.org/uniprot/P11678

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_000502

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_000493

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