TOPBP1 (NM_007027) Human Recombinant Protein

Product Specifications

Background

This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human topoisomerase (DNA) II binding protein 1 (TOPBP1), Lys892-Asp1146, with N-terminal His tag, expressed in E.coli, 50ug

Synonyms

Dpb11; TOP2BP1

Gene ID

11073

UniProt

Q92547, A0AV47, Q05BV8, A7E2X7

Accession Number mRNA

NM_007027

Chromosomal Location

3q22.1

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, pH8.0, 8M Urea

Molecular Weight

28.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.