TOPBP1 (NM_007027) Human Recombinant Protein
Product Specifications
Background
This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq, Jul 2008]
Synonyms
Dpb11; TOP2BP1
Gene ID
11073
UniProt
Q92547, A0AV47, Q05BV8, A7E2X7
Accession Number mRNA
NM_007027
Chromosomal Location
3q22.1
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 8M Urea
Molecular Weight
28.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TOPBP1
Species
Human
Protein ID
NP_008958
Overview
Purified recombinant protein of Human topoisomerase (DNA) II binding protein 1 (TOPBP1), Lys892-Asp1146, with N-terminal His tag, expressed in E.coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11073
Uniprot URL
https://www.uniprot.org/uniprot/Q92547
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007027
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_008958
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