SS18 (NM_001007559) Human Recombinant Protein
Product Specifications
Background
Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (PubMed:29374058) .[UniProtKB/Swiss-Prot Function]
Synonyms
SSXT; SYT
Gene ID
6760
UniProt
Q15532, A0A024RC40
Accession Number mRNA
NM_001007559
Chromosomal Location
18q11.2
Expression System
E. coli
Tag
N-His ABP
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 8M Urea
Function
Druggable Genome
Molecular Weight
18.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SS18
Species
Human
Protein ID
NP_001007560
Overview
Purified recombinant protein of Human synovial sarcoma translocation, chromosome 18 (SS18), transcript variant 1, Gly227-Pro255, with N-terminal His-ABP tag, expressed in E.coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6760
Uniprot URL
https://www.uniprot.org/uniprot/Q15532
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001007559
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001007560
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