SS18 (NM_001007559) Human Recombinant Protein

Product Specifications

Background

Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (PubMed:29374058) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Human synovial sarcoma translocation, chromosome 18 (SS18), transcript variant 1, Gly227-Pro255, with N-terminal His-ABP tag, expressed in E.coli, 50ug

Synonyms

SSXT; SYT

Gene ID

6760

UniProt

Q15532, A0A024RC40

Accession Number mRNA

NM_001007559

Chromosomal Location

18q11.2

Expression System

E. coli

Tag

N-His ABP

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, pH8.0, 8M Urea

Function

Druggable Genome

Molecular Weight

18.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.