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FGF5 (NM_004464) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human fibroblast growth factor 5 (FGF5), transcript variant 1, Gly22-End, with N-terminal His tag, expressed in E.coli, 50ug

Synonyms

HBGF-5; Smag-82; TCMGLY

Gene ID

2250

UniProt

P12034, Q8NBG6

Accession Number mRNA

NM_004464

Chromosomal Location

4q21.21

Expression System

E. coli

Tag

N-His

Related Pathways

MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

Field of Research

MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, pH8.0, 8M Urea

Function

Druggable Genome, Secreted Protein

Molecular Weight

27.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FGF5

Species

Human

Protein ID

NP_004455

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2250

Uniprot URL

https://www.uniprot.org/uniprot/P12034

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004464

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004455

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