FGF5 (NM_004464) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Overview
Purified recombinant protein of Human fibroblast growth factor 5 (FGF5), transcript variant 1, Gly22-End, with N-terminal His tag, expressed in E.coli, 50ug
Synonyms
HBGF-5; Smag-82; TCMGLY
Gene ID
2250
UniProt
P12034, Q8NBG6
Accession Number mRNA
NM_004464
Chromosomal Location
4q21.21
Expression System
E. coli
Tag
N-His
Related Pathways
MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton
Field of Research
MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 8M Urea
Function
Druggable Genome, Secreted Protein
Molecular Weight
27.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FGF5
Species
Human
Protein ID
NP_004455
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2250
Uniprot URL
https://www.uniprot.org/uniprot/P12034
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004464
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004455
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