CD61 (ITGB3) (NM_000212) Human Recombinant Protein

Product Specifications

Background

The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ITGB3), Ser536-Asp718, with N-terminal His tag, expressed in E.coli, 50ug

Synonyms

BDPLT2; BDPLT16; BDPLT24; CD61; GP3A; GPIIIa; GT; GT2

Gene ID

3690

UniProt

P05106

Accession Number mRNA

NM_000212

Chromosomal Location

17q21.32

Expression System

E. coli

Tag

N-His

Related Pathways

Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton

Field of Research

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol

Function

Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

Molecular Weight

20.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.