PGP9.5 (UCHL1) (NM_004181) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.[provided by RefSeq, Sep 2009]
Synonyms
HEL-117; HEL-S-53; NDGOA; PARK5; PGP 9.5; PGP9.5; PGP95; SPG79; Uch-L1
Gene ID
7345
UniProt
P09936, V9HW74
Accession Number mRNA
NM_004181
Chromosomal Location
4p13
Expression System
E. coli
Tag
N-His
Related Pathways
Parkinson's disease
Field of Research
Parkinson's disease
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol
Function
Druggable Genome, Protease
Molecular Weight
24.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UCHL1
Species
Human
Protein ID
NP_004172
Overview
Purified recombinant protein of Human ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1), Met1-Cys220, with N-terminal His tag, expressed in E.coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7345
Uniprot URL
https://www.uniprot.org/uniprot/P09936
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004181
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004172
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