CD21 (CR2) (NM_001877) Human Recombinant Protein
Product Specifications
Background
This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) . Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Overview
Purified recombinant protein of Human complement component (3d/Epstein Barr virus) receptor 2 (CR2), transcript variant 2, Ser603-His718-GGGGS-Trp900-Ser970, with N-terminal His tag, expressed in E.coli, 50ug
Synonyms
C3DR; CD21; CR; CVID7; SLEB9
Gene ID
1380
UniProt
P20023
Accession Number mRNA
NM_001877
Chromosomal Location
1q32.2
Expression System
E. coli
Tag
N-His
Related Pathways
B cell receptor signaling pathway, Complement and coagulation cascades, Hematopoietic cell lineage
Field of Research
B cell receptor signaling pathway, Complement and coagulation cascades, Hematopoietic cell lineage
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
21.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CR2
Species
Human
Protein ID
NP_001868
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1380
Uniprot URL
https://www.uniprot.org/uniprot/P20023
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001877
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001868
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