CD21 (CR2) (NM_001877) Human Recombinant Protein

Product Specifications

Background

This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) . Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]

Overview

Purified recombinant protein of Human complement component (3d/Epstein Barr virus) receptor 2 (CR2), transcript variant 2, Ser603-His718-GGGGS-Trp900-Ser970, with N-terminal His tag, expressed in E.coli, 50ug

Synonyms

C3DR; CD21; CR; CVID7; SLEB9

Gene ID

1380

UniProt

P20023

Accession Number mRNA

NM_001877

Chromosomal Location

1q32.2

Expression System

E. coli

Tag

N-His

Related Pathways

B cell receptor signaling pathway, Complement and coagulation cascades, Hematopoietic cell lineage

Field of Research

B cell receptor signaling pathway, Complement and coagulation cascades, Hematopoietic cell lineage

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol

Function

Druggable Genome, Transmembrane

Molecular Weight

21.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.