NGAL (LCN2) (NM_005564) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice. [provided by RefSeq, Sep 2015]
Synonyms
24p3; MSFI; NGAL; p25
Gene ID
3934
UniProt
P80188
Accession Number mRNA
NM_005564
Chromosomal Location
9q34.11
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol
Function
Secreted Protein
Molecular Weight
20.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
LCN2
Species
Human
Protein ID
NP_005555
Overview
Purified recombinant protein of Human lipocalin 2 (LCN2), Gln21-End, with N-terminal His tag, expressed in E.coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3934
Uniprot URL
https://www.uniprot.org/uniprot/P80188
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005564
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005555
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