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NGAL (LCN2) (NM_005564) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice. [provided by RefSeq, Sep 2015]

Overview

Purified recombinant protein of Human lipocalin 2 (LCN2), Gln21-End, with N-terminal His tag, expressed in E.coli, 50ug

Synonyms

24p3; MSFI; NGAL; p25

Gene ID

3934

UniProt

P80188

Accession Number mRNA

NM_005564

Chromosomal Location

9q34.11

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol

Function

Secreted Protein

Molecular Weight

20.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

LCN2

Species

Human

Protein ID

NP_005555

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3934

Uniprot URL

https://www.uniprot.org/uniprot/P80188

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005564

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005555

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